According to flight tracking website FlightAware.com, 41 flights at Orlando International were canceled and 33 were delayed in a 24 hour period.
Many U.S. carriers are waving change fees for customers who are scheduled to fly to and from airports under the storm's bull's-eye.
American Airlines is waiving change fees for flights to and from certain airports in Ohio, Pennsylvania, New York, Connecticut, Maine, and more.
Airline passengers stand in line as they wait to rebook their canceled flights at the American Airlines counter at Miami International Airport on Monday, March 13, 2017. But most planes scheduled to depart from Boston Tuesday have been called off, as have the majority of planned arrivals. Freezing rain was reported farther south in the mid-Atlantic, including parts of Washington, DC, leading to an accumulation of up to one-quarter inch of ice at Baltimore - Washington International Airport.
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We are sorry for the disruption to your travel plans and are doing all we can to minimise the effect the weather forecast will have on our USA operations.
Delta Airlines canceled flight 948 scheduled to take off at 2:10 pm, from Mexico City to NY as well as flight 752, which connected Aeromexico's AMX121 flight to NY. Many flights out of St. Louis Airport pass through O'Hare or Chicago Midway airports. Even in Florida, about three dozen flights had been canceled in Orlando - mostly on flights to the north.
The airline says it's making every effort to contact and re-accommodate customers on all cancelled flights.
Hundreds of school districts from Buffalo to New York City have cancelled classes and authorities are advising people to stay off the roads as a nor'easter starts to pummel the Northeast.
RDU officials said the airport does not expect the schedule to be normal for at least a day or two.