Both teams have three points with Chile ahead on goal difference after their 2-0 win over Cameroon and Germany's 3-2 victory against Australia. Both the teams will be looking to attack right from the kick off whistle and a free scoring game looks very much on the cards.
Loew, having rested all of his World Cup-winning stars, will match his young guns against an experienced Chile team which won both the 2015 and 2016 Copa America titles.
It will be no surprise if the pair meet again in the Confederations Cup final in St. Petersburg on July 2.
Chile were determined to respond to the equaliser positively and did so as the game got underway after half-time, Alexis Sanchez bending a free-kick just over the bar.
He also said the World Cup winners, Germany, would be tough opponents but Chile planned to be a "real threat" to them on the pitch.
"We knew they would come at us with a lot of pressure and power", said goal-scorer Stindl. "Our mentality is one of our biggest achievements of this team".
The Gunners star made it 1-0 to Chile after a terrible error from his club team-mate Shkodran Mustafi, playing in defence for Germany.
Loew said that goalkeeper Marc-Andre ter Stegen will return to the starting lineup after Bernd Leno played against Australia.More news: Cuba will refuse Trump's demand to send Assata Shakur back to America
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Likewise, Arsenal team-mates Shkodran Mustafi and Sanchez could line up against each other.
When is Germany vs Chile?
The most recent was in 2014 when Mario Goetze's goal sealed a 1-0 friendly win in Stuttgart.
While wrapping up their place in the next round with a win here would have allowed either to rest players in the final group match, both sides remain in a fairly strong position given the gulf in class between themselves, Cameroon and Australia, who sit on just one point apiece.
However, with a point apiece all but guaranteeing qualification for the two teams after Cameroon's draw with Australia, neither went insane in trying to find a victor.
"We will have to be at our top level, because if we lose we are done at this tournament". Firstly, Eduardo Vargas, set up by Arturo Vidal, had his goal disallowed for offside by the VAR to the fury of the scorer as he had already begun his celebrations by the time the call was made.
That early strike from @Alexis_Sanchez was goal no.in #ConfedCup history! Milligan and fellow midfielder Aaron Mooy will be tasked with making sure Australia maintain possession, an area where they struggled against Germany.