The 68-year-old signed a new two-year deal with the Gunners last summer, but calls for him to end his 22-year stay at the club have once again reached fever pitch following a run of four successive defeats across all competitions.
The loss was Arsenal's tenth of the season, meaning the club have already lost more games this term than they did in all of the last campaign.
Arsenal fans were angered by the performance of the players and continued their chants for Wenger to leave his position at the club, although a number of them took to social media to heavily criticise a number of players.
Thierry Henry has insisted he has never backed away from a challenge after being asked if he would be prepared to take over from Arsene Wenger at Arsenal.
Arsenal are now 13 points behind fourth-placed Tottenham with only nine Premier League games to go.More news: Parts of Southern California face mandatory evacuation amid incoming storm
More news: John Oliver Rips Into Trump's Plan to Arm America's Teachers
More news: Illinois River Flooding In Cherokee County
- Pascal Gross has assisted Glenn Murray four times in the Premier League this season - only Cesar Azpilicueta (six for Alvaro Morata) and Kevin De Bruyne (five for Sergio Aguero) have assisted a player more. "We play Sunday, Thursday, Sunday, Sunday... it's almost physically impossible to play this number of games".
Wenger, in a somewhat freaky analogy more befitting the occasional ramblings of compatriot Eric Cantona, the former Manchester United star, added: "When you struggle for confidence, it's hard as well when you have just the pants on..."
Arsenal's defeat on Sunday was their 10th in the Premier League this season.
Their last hope of lifting a trophy and Champions League qualification now rests on winning the Europa League and they face Italian giants AC Milan in the first leg of their last-16 encounter this Thursday. These are always the questions you get when you are in the situation we are in.
"If I had listened to people who were talking about where I was going to be, I would not have been here. I'm long enough in the job to know what's going on and I'm long enough in the job as well to know that what's most important is to make sure you focus on what's important, that you give absolutely your best with full commitment". My worry is to get Arsenal to win football games, and then we see where we go from there.