Wilson was unable to make significant contact with Joshua King's cross, but City did not heed the let-off as the newly-capped England striker powered home a header from Simon Francis' ball into the box.
The winger became the first player to score in his first six Premier League appearances against a single opponent when he put City 2-1 up from close range at Etihad Stadium.
West Ham ended Newcastle's three-match winning run as Javier Hernandez struck twice in a 3-0 victory at St James Park.
Among the goals in that streak was a victor seven minutes into injury time at Bournemouth in the third game of the last season. "They are tough sides".
Predictably, City dominated the ball from the off, and were almost ahead on 11 minutes as Roberto Pereyra's sloppy square pass allowed Sane through on goal, only for Ben Foster to race out and save superbly.
He nearly scored a remarkable individual goal minutes before he did find the net, producing a mazy run past five opponents before seeing his shot deflect off Andrew Surman against the post.
David Wagner's side took just 54 seconds to open the scoring through Mathias Jorgensen.
CLIVE BRUNSKILL GETTYCallum Wilson of AFC Bournemouth scores his team's only goal
However, the hosts were reduced to 10 men after half an hour when Steve Mounie was sent off for a high challenge and Brighton took full advantage with goals by Shane Duffy and Florin Andone.
"We don't expect every 90 minutes to have an incredible performance". The Huddersfield resistance eventually caved further, as Florin Andone scored the victor for Brighton after 69 minutes on his first start for the club.
But that solitary strike against Huddersfield in August remains the only one that Jesus has scored in the league after he fired another blank against Watford before being substituted on 87 minutes.
Michael Obafemi fed Armstrong inside the area and from a tight angle the Scottish worldwide smashed the ball confidently past De Gea for his third goal in two league games. Now, this season he is playing less and it is what it is.
Palace spent much of the match on top without finding another goal, before Andros Townsend's effort flew into the top corner after 77 minutes to seal the win for Roy Hodgson's side.
He made three key passes, more than any other City player, and had an eye for goal, pulling off five of City's 15 shots in total.More news: Klopp fined for wild celebrations after Liverpool victor
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